Spherotech Inc.

INNOVATIVE & EXPERIENCED MICROSPHERE MANUFACTURER

Spherotech was established in 1992 to manufacture and supply uniform microparticles for biomedical and diagnostic applications. Our headquarters are 25 miles north of Chicago in Lake Forest, IL.

As a global supplier of microparticle solutions, our experienced scientists manufacture high quality latex, fluorescent, paramagnetic, ferromagnetic and colored dyed microparticles. Our microsphere portfolio offers you:

• PLAIN POLYSTYRENE BEADS
  • Uniform Shape and Size
  • Multi-liter Capabilities
  • Diameters between 50nm and 200um available
  • Ideal for use in immunoassays such as latex agglutination, particle based enzyme immunoassays, and fluorescent immunoassays

• FUNCTIONALIZED POLYSTYRENE BEADS
  • Provides functional groups such as Carboxyl or Amino for covalent coupling of proteins, ligands, antibodies or antigens to the surface of the microparticles using water soluble carbodiimide as the coupling agent.
  • Can be used to manipulate the orientation of the coated material by passive adsorption by varying particle surface charges using functionalized particles such as hydroxyl, sulfate and dimethylamino
  • Can be coated with polyclonal antibodies by passive adsorption.

• PROTEIN COATED POLYSTYRENE BEADS
  • Manufactured by either passive adsorption or covalent coupling depending upon the intended application
  • Stable for several years under proper storage condition
  • Can be coated with polyclonal antibodies by passive adsorption.
  • Available in a wide variety of formats: polystyrene particles, fluorescent particles and magnetic particles coated with antibodies, Avidin, Streptavidin and Biotin and other proteins.

• FLUORESCENT POLYSTYRENE BEADS
  • Beneficial to bioimaging and biosensing applications
  • Available with functional groups for covalent binding of antigens or antibodies.
  • Uniform and stable fluorescence

• MAGNETIC POLYSTYRENE BEADS
  • Consist of paramagnetic particles prepared by coating a layer of iron oxide and polystyrene onto polystyrene core particles
  • Uniform in size and spherical in shape
  • Separated using a magnet and resuspended when removed from the magnetic field
  • Used for cell separation, affinity purification, DNA probe assays, magnetic particle EIA, etc.

APPLICATIONS FOR MICROBEADS MANUFACTURED BY SPHEROTECH:

• Fluorescence immunoassay
• Enzyme immunoassay (EIA)
• Fluorescence microscopy
• Confocal fluorescence microscopy
• Flow cytometry/ image cytometry
• Magnetic cell separation
• Magnetic particles EIA
• Microfluidics
• Other research and industrial applications.

EXPERTS IN MICROSPHERE MANUFACTURING & RESEARCH AND DEVELOPMENT

Spherotech specializes in microsphere research and development. We constantly introduce new products and improve the existing portfolio. Our loyal customers value Spherotech's agile manufacturing capabilities, custom OEM particle solutions, and value-add supply options. Our manufacturing facilities can accommodate multi-liter lot sizes of our entire microsphere offering.

Our world class quality and technical support are standard practice. As an ISO 9001:2008 registered company, we consistently meet or exceed customer expectations. Spherotech's scientists look forward to meeting your application specific requirements in microsphere technology.

While we publish an overview of our products, it is by no means comprehensive. If the particle you require is not listed, we urge you to contact our team to check our complete inventory.